第12回国際シンポジウム「味覚嗅覚の分子神経機構」

日時:平成26年11月2日(日)9:50 ~17:30
        11月3日(月)9:00 ~16:30
会場:九州大学 馬出病院キャンパス コラボステーション1(2F 視聴覚ホール:シンポジウム)
   コラボステーション2(1F コミュニティーラウンジ:ポスター)
主催:九州大学 味覚・嗅覚センサ研究開発センター/化学感覚研究会/
   九州大学歯学研究院「口腔健康科学」プロジェクト

2nd, November, 2014

■ Session I 10:00 – 12:25
Detection and transmission of chemosensory signals
[Chair: Takatoshi Nagai (Keio Univ) and Satoshi Wakisaka (Osaka Univ)]

IS1-1 10:00 – 10:35 (invited talk)
Neurotransmitters in taste buds: ATP revisited, reviewed, and revised
Stephen D. Roper
Miller School of Medicine, University of Miami, Miami, FL 33136 USA

IS1-2 10:35 – 11:10 (invited talk)
Separate progenitors for taste bud cell types
Nirupa Chaudhari
Dept of Physiology & Biophysics and Program in Neurosciences, University of Miami Miller School of Medicine, Miami, FL, USA

IS1-3 11:10 – 11:35 (invited talk)
Gustatory innervation in taste bud is stable without presynaptic cells for the rapid reconnection to the ever-renewing taste receptor cells
Noriyuki Nakashima
Dept. Physiol., Grad. Sch. Med., Kyoto Univ., Kyoto, Japan

IS1-4 11:35 – 11:55
Interspecific variation of ligand sensitivity and evolution of bitter taste receptors TAS2R1 and TAS2R4 in New World monkeys
Kei Tsutsui,1 Masahiro Otoh,2 Kodama Sakurai,2 Nami Suzuki-Hashido,1 Takashi Hayakawa,2 Barbara J. Welker,3 Filippo Aureli,4,5 Colleen M. Schaffner,5 Linda M. Fedigan,6 Shoji Kawamura,2 Hiroo Imai1
1Primate Research Institute, Kyoto University, Japan; 2The University of Tokyo, Japan; 3State University New York Geneseo, USA; 4Liverpool John Moores University, UK; 5Universidad Veracruzana, Mexico; 6University of Calgary, Canada.

IS1-5 11:55 – 12:25 (invited talk)
The taste receptor repertoire, expression and function in pigs
Eugeni Roura
Centre for Nutrition and Food Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Australia

■ Session II 14:00 – 15:25
From peripheral chemoreceptors to the central nervous system
[Chair: Kumiko Sugimoto (Tokyo Med Dent Univ) and Takenori Miyamoto (Japan Women’s Univ)]

IS2-1 14:00 – 14:35 (invited talk)
Nicotinic Acetylcholine Receptor Mediated Bitter Taste of Nicotine and Alcohol
Vijay Lyall, Shobha Mummalaneni and Jie Qian
Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, VA 23219

IS2-2 14:35 – 14:55
Exploring the neural representation of salt taste in the rat chorda tympani nerve with stereotrodes
Masashi Inoue, Natsuki Sugano, Tetsuhiro Kobayashi, Hiroyuki Minezumi and Hiroyoshi Miyakawa
Laboratory of Cellular Neurobiology, Tokyo University of Pharmacy and Life Sciences, Hachioji 192-0392, Japan

IS2-3 14:55 – 15:25 (invited talk)
Oscillation and synchronization of neuronal activity in the insular cortex implicated in the feeding behavior
Youngnam Kang, Hajime Sato, Tsutomu Kawano, Mitsuru Saito, Hiroki Toyoda
Dept Neurosci & Oral Physiol, Osaka University Graduate School of Dentistry

■ Session III 15:40 – 17:30
Oral / gut / brain interaction for energy homeostasis
[Chair: Yuzo Ninomiya (Kyushu Univ) and Kunio Torii (Torii Nutrient-Stasis Institute Inc.)]
IS3-1 15:40 – 16:15 (invited talk)
Intestinal brush border enzymes in sweet taste cells
Robert F Margolskee
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA.

IS3-2 16:15 – 16:35
Multiple methods to characterize endoderm-derived tissues
Ken Iwatsuki
Department of Nutritional Science and Food Safety, Faculty of Applied Bioscience
Tokyo University of Agriculture, Tokyo, Japan

IS3-3 16:35 – 16:55
Loss of gastrointestinal brush cells in Skn-1-deficient mice reduces insulin secretion
Yoshiro Ishimaru1, Misako Yoshioka1, Tomiko Asakura1, Keiko Abe1
1Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan

IS3-4 16:55 – 17:30 (invited talk)
Gut-brain nutrient sensing circuits in the integrated control of energy balance
Gary J. Schwartz
Departments of Medicine & Neuroscience, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10463 USA

3rd, November, 2014

■ Session IV 09:10 – 12:20
Olfaction
[Chair: Kazushige Touhara (Univ of Tokyo) and Yoshihiro Yoshihara (RIKEN)]

IS4-1 09:10 – 09:50 (invited talk)
Perceived Odor Qualities
Andreas Keller
The Rockefeller University

IS4-2 09:50 – 10:10
Bcl11b regulates the class selection of olfactory sensory neurons
Takayuki Enomoto1, Hidefumi Nishida2, Tetsuo Iwata2, Makoto Ohmoto3, Akito Fujita2, Ryota Nakamura2, Yukio Mishima4, Ryo Kominami4, Ichiro Matsumoto3 and Junji Hirota1, 2
1Center for Biological Resources and Informatics, Tokyo Institute of Technology, Yokohama 226-8501, Japan ,2Department of Bioengineering, Graduate School of Bioscience and Bioengineering, Tokyo Institute of Technology, Yokohama 226-8501, Japan, 3Monell Chemical Senses Center, Philadelphia, PA19104, USA, 4Department of Molecular Genetics, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8122, Japan

IS4-3 10:10 – 10:30
Transcription factor Npas4 regulates the sensory experience-dependent development of dendritic spines in newborn olfactory bulb interneurons
Takahashi H, Yoshihara S, Kinoshita M, Asahina R and Tsuboi A
Lab for Mol Biol of Neural System, Nara Med Univ, Kashihara, Japan

IS4-4 10:30 – 10:50
Sema7A-PlxnCl signaling is essential for triggering olfactory synapse formation
Nobuko Inoue1,4, Hiromi Naritsuka2, Hiroshi Kiyonari3, Hirofumi Nishizumi1 and Hitoshi Sakano1,4
1 Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan, 2 Department of Physiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan, 3 RIKEN Institute, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan, 4 Department of Brain Function, University of Fukui School of Medicine, 23-3, Shimo-aizuki, Matsuoka, Fukui 910-1193, Japan

IS4-5 11:00 – 11:20
Motivation maps in the mouse olfactory tubercle
Koshi Murata, Michiko Kanno, Nao Ieki, Kensaku Mori, and Masahiro Yamaguchi
Department of Physiology, Graduate School of Medicine, the University of Tokyo, JST-CREST

IS4-6 11:20 – 11:40
ATP acts as an attractive odorant for zebrafish
Noriko Wakisaka, Yoshihiro Yoshihara
RIKEN Brain Science Institute, Wako, Japan

IS4-7 11:40 – 12:00
Light and pheromone sensoryneuron regulates temperature habituation in C. elegans
Atsushi Kuhara, Tomoyo Ujisawa, Satoru Sonoda, Misaki Okahata, Akane Ohta
Institute for Integrative Neurobiology, Konan University

IS4-8 12:00 – 12:20
A highly accurate cancer diagnosis system using C. elegans scent detection
Takaaki Hirotsu1, Hideto Sonoda2, Takayuki Uozumi1, Koshi Mimori3, Yoshihiko Maehara4, Masayuki Hamakawa1
1Department of Biology, Graduate School of Sciences, Kyushu University, 2Department of General Surgery, Imari-Arita Kyoritsu Hospital, 3Department of Surgery, Kyushu University Beppu Hospital, 4Departments of Surgery and Science, Graduate School of Medical Sciences, Kyushu University

■ Session V 14:00 – 16:20
Ingestive Behavior
[Chair: Teiichi Tanimura (Kyushu Univ) and Mamiko Ozaki (Kobe Univ)]

IS5-1 14:00 – 14:30 (invited talk)
Axonal transport of insulin receptor in the salt-sensing neuron mediates taste avoidance learning in C. elegans
Yuichi Iino
Department of Biological Sciences, Graduate School of Science, the University of Tokyo

IS5-2 14:30 – 15:00 (invited talk)
Functional Interaction between TRP channels and Anoctamin1
Makoto Tominaga1,2, Yasunori Takayama 1
1Division of Cell Signaling, Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences), National Institutes of Natural Sciences, 2The Graduate University for Advanced Studies (SOKENDAI)

IS5-3 15:00 – 15:20
The involvement of the brain reward system and amygdala in the retrieval of conditioned taste aversion
Tadashi Inui
Behavioral Physiology, Human Sciences, Osaka University

IS5-4 15:20 – 15:50 (invited talk)
Biological significance of glutamate signaling for homeostasis and healthier life
Kunio Torii
Torii Nutrient-Stasis Institute Inc., Japan

IS5-5 15:50 – 16:20 (invited talk)
The odor of Osmanthus fragrans attenuates food intake
Takashi Yamamoto
Faculty of Health Science, Kio University, Nara 635-0832, Japan